Artima posted a 6-part series of interviews with Guido van Rossum (weblog), creator of Python. Here are the six parts in order.

The Making of Python
Python creator Guido van Rossum talks with Bill Venners about Python's history, the influence of the ABC language, and Python's original design goals.

Python's Design Goals
Python creator Guido van Rossum talks with Bill Venners about Python's original design goals—how he originally intended Python to "bridge the gap between the shell and C," and how it eventually became used on large scale applications.

Programming at Python Speed
Python creator Guido van Rossum talks with Bill Venners about the source of Python's famed programmer productivity and the joys of exploring new territory with code.

Contracts in Python
Python creator Guido van Rossum talks with Bill Venners about the nature of contracts in a runtime typed programming language such as Python.

Strong versus Weak Typing
Python creator Guido van Rossum talks with Bill Venners about the robustness of systems built with strongly and weakly typed languages, the value of testing, and whether he'd fly on an all-Python plane.

Designing with the Python Community
Python creator Guido van Rossum talks with Bill Venners about the importance of "pythonic" API design, the usefulness of intuiting performance, the value of experience and community feedback in design decisions, and the process of deciding how to evolve Python's standard library.